PICK:WASHINGTON COMMANDERS +6.5 (-106)

The Commanders have been a surprise this season, but beating the Ravens in Baltimore seems unlikely, especially with Lamar Jackson poised for a big game. Baltimore’s offense has been in strong form, delivering consistently over the past three weeks and should be able to exploit Washington's defense. While the Ravens are expected to win, the Commanders, as 6.5-point underdogs, could still keep the game close.

PICK:ARIZONA CARDINALS +5.5 (-112)

Pro Football Network: Packers 27, Cardinals 23 "This has the makings of being a high-scoring game, but that is very much baked into the 50-point total. The Packers are the better team, and taking their moneyline as part of a parley is the top play." Arizona Republic: Packers 27, Cardinals 23 "Kyler Murray and the Arizona Cardinals impressed in their Week 5 win over the 49ers but winning at Lambeau on the road early in the morning will be too difficult a task."

PICK:NEW ENGLAND PATRIOTS +7 (-113)

The Patriots have struggled offensively this season, particularly with their offensive line, making it likely that the Texans can pressure Drake Maye or Jacoby Brissett into mistakes. Houston, 1-1 on the road this season, has seen better performances from C.J. Stroud away from home. While the Texans are favored to win, New England's ability to force turnovers may keep the game close, even as Houston looks to capitalize on the Patriots' offensive woes.

PICK:UNDER 36 (-111)

The Chargers and Broncos both have struggling offenses but strong defenses, ranking in the top five for defensive DVOA. With their tendency for low-scoring games, the under seems likely, especially given that games with a total of 37 or below have hit the under 73% of the time since November 2019. Denver, riding a three-game win streak, is favored to win 21-17, with their defense expected to be the key factor against the Chargers, who have lost two straight games.

PICK:SEATTLE SEAHAWKS +3.5 (-114)

The 49ers, despite a 2-3 record, rank fifth in net expected points added per game, though they've only beaten weaker teams like the Jets and Patriots. Seattle's 3-0 start was aided by a weak schedule, and while Geno Smith has overperformed, their defense remains mediocre. However, Seattle’s strong home-field advantage makes them a compelling pick against a struggling 49ers team.